Dr. Ian Rockett began the webinar by providing information about suicide misclassification, especially as it relates to poisoning and the current opioid epidemic. He also discussed this misclassification as a problem for understanding and preventing suicide and then explained the concept of death from drug self-intoxication (DDSI) and the need for an enhanced category of self-injury mortality that transcends registered suicides. Dr. Eric Caine built on the prior presentation by placing this work into a public health-prevention context. Of note, many programmatic efforts – e.g., preventing suicide or DDSI – are based on the manner of death and the factors that were apparent during the last moments of life. Prevention efforts for self-injury mortality, however, must be developed long before these final, fatal moments.